Cardiac Surgery and Medical Devices

Diabetic Cardiomyopathy – Addressing a Growing Cardiometabolic Challenge

The rising global incidence of diabetes and obesity has significantly contributed to the increased prevalence of diabetic cardiomyopathy—a distinct form of heart disease marked by myocardial fibrosis, structural remodeling, and progressive cardiac dysfunction, independent of hypertension or coronary artery disease. Unlike traditional cardiovascular complications, diabetic cardiomyopathy presents unique pathophysiological challenges, including altered glucose metabolism, oxidative stress, and chronic low-grade inflammation. Current research is emphasizing the identification of early biomarkers and advanced imaging techniques, such as cardiac MRI and speckle-tracking echocardiography, to enable timely diagnosis before irreversible damage occurs. Future therapeutic strategies are focused on precision-targeted approaches, including metabolic modulation, anti-fibrotic agents, and gene-based therapies to halt or reverse myocardial injury. Moreover, integrated care models that combine glycemic control, lifestyle modification, and cardiovascular monitoring are essential in reducing the burden of heart failure among diabetic individuals. Addressing diabetic cardiomyopathy is crucial for improving long-term outcomes in this high-risk population.